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Epistaxis

NICE CKS Epistaxis. Last revised Oct 2024.

Epistaxis

Epistaxis, commonly known as a nosebleed,  refers to bleeding from the nasal cavity. It is a symptom or presentation, rather than a condition.

This updated UKMLA guide to epistaxis is based on NICE CKS, which covers anterior vs posterior epistaxis, causes,  assessment, and management.

Classification

Type Implicated vessel Description
Anterior epistaxis Kiesselbach plexus (Little’s area of the anterior nasal septum) 80-95% cases

Bleeding is less severe and the bleeding site can often be identified on examination

Posterior epistaxis Branches of the sphenopalatine artery in the posterior nasal cavity Usually seen in older patients

Features suggestive of posterior epistaxis:

  • Profuse bleeding from both nostrils
  • Bleeding site cannot be identified on examination
  • Bleeding first started down the throat

Causes

Most episodes of epistaxis are self-limiting and harmless, and the cause of damage to the blood vessels is not identified.

Local causes of damage to blood vessels:

  • Trauma
    • Nose picking (common)
    • Nasal fractures / blunt trauma (e.g. falls in children)
    • Foreign body
  • Vascular causes
    • HHT
    • GPA
  • Tumours (e.g. nasopharyngeal carcinoma, angiofibroma)
  • Inflammation (e.g. chronic sinusitis, nasal polyps)
  • Cocaine abuse – classically causes septal ulceration +/- perforation
  • Post-operative bleeding (e.g. following ENT, maxillofacial, ophthalmic surgery)
  • Nasal oxygen therapy (esp. long-term use)

General causes of vessel damage (non-specific):

  • Clotting disorder (e.g. vWD, leukaemia, thrombocytopaenia)
  • Antiplatelet or anticoagulant use
  • Atherosclerosis
  • Excessive alcohol consumption
  • Environmental factors (temperature, humidity, altitude, exposure to irritants)

Assessment

Examine both nasal passages (ideally with adequate lighting and a nasal speculum)

  • Look for a bleeding point

Features suggestive of posterior epistaxis:

  • Profuse bleeding from both nostrils
  • Bleeding site cannot be identified on examination
  • Bleeding first started down the throat

Laboratory investigations are not usually required unless an underlying cause is suspected:

  • Consider FBC if bleeding has been heavy or recurrent, or anaemia is suspected
  • Only perform coagulation studies if a clotting disorder is suspected or the patient takes warfarin

Management

Acute Epistaxis

Referral criteria:

  • Haemodynamically unstable → immediate transfer to A&E
  • Posterior epistaxis suspected → admit to hospital

If immediate referral is not necessary:

Steps Management Description
Step 1 First aid measures
  • Sit up + tilt forward (avoid lying down, unless feeling faint)
  • Pinch the soft cartilaginous part of the nose firmly for 10-15 mins without releasing the pressure
  • Keep the mouth open and breathe through the mouth

If the bleeding did not stop after 10-15 min → proceed to step 2

Step 2 Nasal cautery or nasal packing Depends on whether the bleeding point is identifiable:

  • Identifiable → silver nitrate nasal cautery (avoid in younger children)
    • If ineffective → nasal packing
  • NOT identifiable → nasal packing + admit to hospital

If nasal cautery and nasal packing are not available in primary care → admit to hospital

Step 3 (if the above failed) Secondary care management Options include:

  • Endoscopic assessment and electrocautery
  • Formal packing (maybe under GA)
  • Radiological arterial embolisation
  • Examination under anaesthesia + surgical intervention (e.g. diathermy, septal surgery, arterial ligation, laser treatment)
  • Tranexamic acid

Complications of Treatment

Treatment Potential complications
Nasal cautery
  • Septal perforation

Therefore, avoid performing on both sides of the septum

Nasal packing
  • Sinusitis
  • Septal haematoma / abscess
  • Pressure necrosis
  • Toxic shock syndrome (from prolonged packing)

Management After Resolution

If the bleeding stops with first aid measures:

  • Consider Naseptin® (chlorhexidine and neomycin) cream – QDS for 10 days
  • If allergic to neomycin / peanuts / soya → consider mupirocin nasal ointment

If the bleeding stops with nasal cautery:

  • Dab the cauterised area with a clean cotton bud
  • Apply Naseptin® (chlorhexidine and neomycin) cream – QDS for 10 days
  • Observe the patient for 15 min to ensure bleeding is controlled
  • Advise the person to avoid blowing their nose for a few hours

After nasal packing:

  • Admit for observation

Recurrent Epistaxis Management

Advise the person on first aid measures to control bleeding during an acute episode

Determine if there is an underlying cause for epistaxis:

  • Consider FBC
  • If < 2 y/o → consider referral to a paediatrician as an underlying cause is likely

If an underlying cause is unlikely:

  • 1st line: topical Naseptin® (chlorhexidine and neomycin) cream QDS for 10 days
    • If allergic to neomycin / peanus / soya → consider mupirocin nasal ointment
  • 2nd line: nasal cautery

References

Related Article

Von Willebrand Disease (VWD)

Warfarin

Acute Leukaemia

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