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Allergic Conjunctivitis

NICE CKS Conjunctivitis – allergic. Last revised: May 2022.

Background Information

Clinical Features

Hallmark of allergic conjunctivitis: bilateral ocular itching (may also be described as burning or stinging).

Other clinical features:

  • Watery or mucoid discharge
  • Hyperaemia injection (conjunctival redness)
  • Chemosis (conjunctival swelling)
  • Eyelid oedema

Allergic conjunctivitis often co-exists with other atopic conditions, the atopic triad:

  • Atopic dermatitis (eczema)
  • Asthma
  • Allergic rhinitis

Guidelines

Investigation and Diagnosis

First, exclude red flags of a red eye warranting referral. See Red Eye Referral

Allergic conjunctivitis is a clinical diagnosis​​​​​, investigations are not normally required.

Management

General Management / Conservative Management

Advise the patient on:

  • Allergen avoidance
  • Avoid rubbing the eyes

Symptomatic management measures:

  • Application of cold compresses to the eyes
  • Application of ocular surface lubricants (e.g. artificial tears and saline solution)

Pharmacological Management

1st line:

  • Topical antihistamine (e.g. anatazoline, also contains xylometazoline), or

 

  • Dual action mast cell stabiliser / topical antihistamine (e.g. azelastine, epinastine, ketotifen, olopatadine)
    • Examples of mast cell stabilisers: sodium cromoglicate, lodoxamide

2nd line:

  • Consider adding topical ocular dicofenac

References

Original Guideline

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