Allergic Conjunctivitis
NICE CKS Conjunctivitis – allergic. Last revised: May 2022.
Article Last Updated:27/10/2025
Background Information
Clinical Features
Hallmark of allergic conjunctivitis: bilateral ocular itching (may also be described as burning or stinging).
Other clinical features:
- Watery or mucoid discharge
- Hyperaemia injection (conjunctival redness)
- Chemosis (conjunctival swelling)
- Eyelid oedema
Allergic conjunctivitis often co-exists with other atopic conditions, the atopic triad:
- Atopic dermatitis (eczema)
- Asthma
- Allergic rhinitis
Guidelines
Investigation and Diagnosis
First, exclude red flags of a red eye warranting referral. See Red Eye Referral
Allergic conjunctivitis is a clinical diagnosis, investigations are not normally required.
Management
General Management / Conservative Management
Advise the patient on:
- Allergen avoidance
- Avoid rubbing the eyes
Symptomatic management measures:
- Application of cold compresses to the eyes
- Application of ocular surface lubricants (e.g. artificial tears and saline solution)
Pharmacological Management
1st line:
- Topical antihistamine (e.g. anatazoline, also contains xylometazoline), or
- Dual action mast cell stabiliser / topical antihistamine (e.g. azelastine, epinastine, ketotifen, olopatadine)
- Examples of mast cell stabilisers: sodium cromoglicate, lodoxamide
2nd line:
- Consider adding topical ocular dicofenac