Scabies
NICE CKS Scabies. Last revised: May 2025.
Guidelines
Investigation and Diagnosis
Usually clinical diagnosis.
If equipment and expertise allow, tests can be done to provide a definitive diagnosis:
- Ink burrow test (black or blue ink applied to the lesion and wiped off to remove surface ink)
- +ve Finding: dark zigzagged line running across and away from the lesion (due to ink tracking down the mite burrow)
- Skin scrapings microscopy
- Presence of mites / eggs / mite faecal material confirms the diagnosis
Management
Seek specialist advice if:
- <2 months (rare in this age group and permethrin cream is only licensed for ≥2 months)
- Crusted scabies (hospital admission may be required and investigation for underlying immunodeficiency)
General / Conservative Management
Advise that bedding, clothing, and towels (and those of all potentially infested contacts) should be decontaminated by washing at a high temperature (at least 60°C) and drying in a hot dryer, or dry-cleaning, or by sealing in a plastic bag for at least 72 hours
Anti-Scabies Treatment
Offer:
- Permethrin 5% cream, or
- Single dose oral ivermectin 200 mcg/kg
Both have similar effectiveness, choose based on the following patient factors
- Avoid permethrin if
- <2 y/o (unlicensed in <2 months)
- Pre-existing eczema or other skin conditions which may lead to hypersensitivity
- Avoid ivermectin if
- Pregnant and breastfeeding
- Severe hepatic impairment
- <15 kg
Advise that itching may continue for up to 4 weeks after successful treatment of scabies. Patients should seek medical advice if itching persists >2-4 weeks after the last treatment application.
Contact Management
All the following should be treated with anti-scabies treatment, even if asymptomatic:
- Household members
- Sexual partners within the past month
- Any other close personal contacts
Post-Scabetic Itch
- Crotamiton 10% cream
- If scabies mites have definitely been eradicated: topical hydrocortisone 1%
Also consider nighttime sedating antihistamine (e.g. chlorphenamine) to improve sleep and reduce scratching