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Sprains and Strains – Overview

NICE CKS Sprains and strains. Last revised: Jun 2025.

Sprains and Strains

Definitions and Anatomy

Term Definition Typical sites
Sprain Stretching and/or tearing of a ligament Ankle, knee, wrist, thumb
Strain Stretching and/or tearing of muscle fibres and/or tendon Calf, hamstrings, quadriceps, back

Key anatomy:

  • Ligaments connect bone to bone and stabilise joints
  • Tendons connect muscle to bone and transmit muscle force
  • Muscles generate movement and may be injured by overstretching or sudden forceful contraction

Common Mechanisms

Sprain

Usually occurs when a joint is forced beyond its normal range of movement, causing ligament injury.

Common examples:

  • Ankle inversion injury → lateral ankle sprain
  • Ankle eversion injury → medial ankle sprain
  • Twisting knee injury → collateral ligament or cruciate ligament injury
  • Fall onto an outstretched hand → wrist or thumb ligament injury

Strain

Usually occurs due to excessive stretching or sudden contraction of a muscle-tendon unit.

Common examples:

  • Sprinting / sudden acceleration → hamstring strain
  • Jumping or pushing off → calf strain
  • Lifting or twisting → back strain

Clinical Features

Feature Sprain Strain
Main structure injured Ligament Muscle or tendon
Pain location Usually around a joint Usually over a muscle belly or tendon
Mechanism Twisting, rolling, forced joint movement Overstretching, sudden contraction, overuse
Swelling / bruising Common around the joint May occur over the injured muscle
Weakness May occur due to pain or instability Common due to muscle injury
Instability May suggest significant ligament injury Not typical unless associated with tendon rupture
Muscle spasm / cramping Less typical More typical

Initial Management

Most simple sprains and strains are managed conservatively.

Early Management: PRICE

Advise on initial PRICE self-management strategies for the first 48-72 hours after injury:

Component Meaning
Protection Protect from further injury (e.g. splinting, taping, appropriate footwear)
Rest Avoid activity for the first 48-72 hours
Ice Apply ice wrapped in a damp towel for 15-20 minutes every 2-3 hours during the day

  • Do NOT apply ice directly over the skin
  • Do NOT leave the wrapped ice over the body part whilst asleep
Compression Use a simple elastic bandage or an elasticated tubular bandage to control swelling (remove before going to sleep)
Elevation Elevate the injured limb above heart level where possible, until the swelling is controlled

Analgesia

  • Paracetamol can be used for pain relief
  • Consider topical NSAIDs
  • Oral NSAIDs may be considered if appropriate, but avoid or use cautiously in patients with contraindications, e.g. renal disease, peptic ulcer disease, anticoagulation, significant cardiovascular risk, or pregnancy.

Early mobilisation

Patients should be advised to start active mobilisation and flexibility (range of motion) exercises as soon as tolerated without excessive pain.

  • Prolonged complete rest may lead to stiffness and delayed functional recovery

Consider referral to physiotherapy if there are ongoing symptoms that are not improving despite self-management strategies

References

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