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Pelvic Organ Prolapse (POP)

NICE guideline [NG123] Urinary incontinence and pelvic organ prolapse in women: management. Last updated: Jun 2019.

NICE guideline [NG210] Pelvic floor dysfunction: prevention and non-surgical management. Published: Dec 2021.

Pelvic Organ Prolapse (POP)

Pelvic organ prolapse (POP) occurs when one or more pelvic organs descend from their normal position into or through the vagina because the pelvic floor support structures become weakened. It may involve the bladder, uterus, vaginal vault, rectum, or bowel.

This updated UKMLA guide to POP is based on NICE NG123 and NG 210, which covers types, staging, risk factors, symptoms, diagnosis, and management.

Definition

POP refers to the descent or herniation of pelvic organ(s) from their normal anatomical position into or through the vagina due to weakness of the pelvic floor support structures.

Classification

Classification by Anatomy

Compartment Type of Prolapse Description / Structure Involved
Anterior Cystocele Herniation of the bladder into the anterior vaginal wall
Urethrocele Herniation of the urethra into the anterior vaginal wall. Often occurs with cystocele (cystourethrocele)
Apical Uterine prolapse Descent of the uterus and cervix down into the vaginal canal
Vaginal vault prolapse Prolapse of the vaginal apex after hysterectomy
Posterior Rectocele Herniation of the rectum into the posterior vaginal wall
Enterocele Herniation of the small bowel into the upper posterior vaginal wall, typically through the pouch of Douglas

Classification by Severity

NICE recommends using the Pelvic Organ Prolapse Quantification (POP-Q) system:

Stage Description (location of the most distal part of prolapse)
0 No prolapse
1 >1 cm above the hymen
2 Within +/-1 cm of the hymen (1cm above or 1cm below)
3 >1 cm below the hymen but NOT fully outside the vagina
4 Complete eversion – visible outside the vagina

Causes and Risk Factors

POP results from weakening of the pelvic floor support structures (muscles, fascia and ligaments) that maintain pelvic organ position.

Established risk factors: [Ref]

  • Vaginal childbirth
  • Advancing age
  • Obesity

Other potential risk factors: [Ref]

  • Chronic constipation
  • Parity (irrespective of mode of delivery)
  • Heavy lifting occupations
  • Previous hysterectomy
  • Connective tissue disorders

Clinical Features

POP is common, and many mild cases are asymptomatic.

Common symptoms in advanced POP:

Vaginal
  • Sensation (or seeing) a bulge / protrusion
  • Pressure
  • Heaviness
Urinary
  • Frequency
  • Urgency
  • Sensation of incomplete emptying
  • Hesitancy
  • Incontinence
  • Having to manually reduce the prolapse or change position to start or complete voiding
Bowel
  • Difficulty opening bowels / straining
  • Sensation of incomplete evacuation
  • Sudden urgency to defecate
  • Bowel incontinence
Sexual
  • Dyspareunia

Investigation and Diagnosis

POP is primarily diagnosed clinically [Ref]

  • Perform a pelvic examination in the dorsal lithotomy position with the patient performing a Valsalva manoeuvre+/- on standing or squatting
  • Use a Sims speculum (split / half speculum) to assess the anterior, posterior and apical vaginal compartments one at a time
  • Assess pelvic floor muscle strength

Do NOT routinely perform imaging if prolapse is detected on physical examination.

Management

1st Line: General / Conservative Management

Category Description / management
Lifestyle modifications Offer to ALL patients:

  • Lose weight if BMI >30 kg/m2
  • Minimise heavy lifting
  • Prevent / treat constipation
Pelvic floor muscle exercises (e.g. Kegel exercises) Supervised pelvic floor muscle training programme (at least 16 weeks) is 1st line for symptomatic stage 1 and 2 POP
Vaginal pessary Consider a pessary in all stages of POP

  • Can be inserted in a clinic
  • Advise to remove once every 6 months (to prevent and monitor for complications like ulceration, infection or displacement)

All symptomatic POP patients should be offered nonsurgical management first, which includes pelvic floor muscle training and/or a pessary trial. [Ref]

2nd Line: Surgical Management

Offer surgery if symptoms persist despite non-surgical options or declined non-surgical options.

Type of prolapse Surgical options
Uterine prolapse
  • Vaginal hysterectomy +/- vaginal sacrospinous fixation
  • Vaginal sacrospinous hysteropexy
  • Manchester repair
  • Sacrohysteropexy
Vault (vaginal) prolapse
  • Vaginal sacrospinous fixation
  • Sacrohysteropexy
Anterior wall prolapse
  • Anterior colporrhaphy
Posterior wall prolapse
  • Posterior colporrhaphy

Consider colpocleisis in:

  • Uterine / vault prolapse, and
  • Frail for surgery, or vaginal sex not intended

References

Related Articles

Urinary Incontinence in Women

Constipation (Adults)

Menopause

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