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Total Live Articles: 381

Gangrene

⚠️ Article status: Temporary high-yield summary

  • This article will be fully reviewed, expanded, and referenced in due course
  • Current content focuses on core principles and exam-relevant concepts
Type Mechanism Key causes Clinical features
Dry gangrene Chronic ischaemia → necrosis with NO infection
  • Most common: PAD
  • Diabetes
  • Atherosclerosis
  • Frostbite
  • Dry, black tissue
  • Well-demarcated
  • No purulence
Wet gangrene Ischaemia + secondary bacterial infection
  • Infected diabetic foot ulcer
  • Necrotising fascitis
  • Swollen, wet tissue
  • Poorly demarcated
  • Foul-smelling
  • Systemic upset (e.g. fever)
Gas gangrene Clostridial toxin-mediated muscle necrosis with gas production

Most common: Clostridium perfringes

  • Trauma
  • Contaminated wounds
  • Surgery
  • Severe pain (out of proportion)
  • Crepitus on palpation
  • Rapid progression
  • Systemic toxicity

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