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Antenatal Care

NICE guideline [NG201] Antenatal care. Published: Aug 2021.

NHS: Pregnancy: Pregnancy (antenatal) care, checks and screening tests: Your antenatal appointments. Last revised: Apr 2023.

Antenatal Timetable / Schedule

Disclaimer:

This does NOT represent the full antenatal timetable and has been condensed and simplified for educational and exam purposes.

Key exam-relevant points are highlighted in bold.

1st Trimester (≤ 12 Weeks)

Gestation (weeks) Key actions Routine checks
8-12 Booking appointment

  • Full history and risk assessment
  • Booking bloods
    • FBC
    • Blood group (including Rhesus D status)
    • Antibody screen
  • Infection screen
    • HIV
    • Syphilis
    • Hepatitis B
    • Rubella immunity status
  • Haemoglobinopathy screen
    • Thalassaemia (all patients)
    • Sickle cell (depends on prevalence)
  • Blood pressure
  • Urinalysis
  • Height, weight and BMI
  • Mental health screen
11-14 1) Dating scan – ultrasound

  • Confirm viability
  • Determine gestational age (by measuring crown-rump length)
  • Detect multiple pregnancy

2) Combined test

  • Screens for Down, Edwards and Patau syndromes
  • Based on maternal age, beta-hCG, PAPP-A and nuchal translucency (see the Fetal Anomaly Screening Programme for more information)

2nd Trimester (13-27 Weeks)

Gestation Key actions Routine checks
16 Review and discuss test results (booking bloods, screening tests) + give information on anomaly scan

Consider iron supplementation if anaemia identified on FBC (see the Anaemia in Pregnancy article for more information)

  • Blood pressure
  • Urinalysis
18-21 1) Anomaly scan (ultrasound to screen 11 structural conditions – see the Fetal Anomaly Screening Programme for more information)

2) Offer whooping cough (pertussis) vaccine

25 This is only necessary in 1st pregnancy (i.e. only in nulliparity but not in multiparity)

  • Discuss fetal movements + when to seek help
  • Advice on antenatal classes
  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal heart auscultation
24-28 Offer OGTT to screen for gestational diabetes if at risk – ANY of the following:

  • Previous gestational diabetes
  • Previous macrosomic baby (≥4.5 kg)
  • 1st degree relative with diabetes mellitus
  • Ethnicity with high prevalence of diabetes mellitus
  • BMI >30 kg/m2

See the Diabetes in Pregnancy article for more information

3rd Trimester (≥ 28 Weeks)

Gestation Key actions Routine checks (basically the same throughout)
28 1) Repeat FBC, blood group (including Rhesus), antibody screen

2) 1st anti-D prophylaxis if Rhesus -ve and non-sensitised

3) Offer RSV vaccine

4) Discuss labour, birth and newborn care

  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal movements
31 This is only necessary in 1st pregnancy (i.e. only in nulliparity but not in multiparity)
  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal movements
34 1) 2nd anti-D prophylaxis if Rhesus -ve and non-sensitised

2) Discuss birth plan

  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal movements
36 Check fetal presentation

If breech presentation → discuss options (ECV vs elective C-section vs breech vaginal delivery) (see the Breech Presentation article for more information)

Provide information: breastfeeding, newborn screening, vitamin K, postnatal mental health

  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal movements
38 Review birth preferences

Discuss post-dates management options

  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal movements
40 This is only necessary in 1st pregnancy (i.e. only in nulliparity but not in multiparity)

  • Reinforce post-dates information
  • Discuss induction of labour
  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal movements
41 Offer membrane sweep

Discuss and offer induction of labour (see the Induction of Labour article for more information)

  • Blood pressure
  • Urinalysis
  • SFH
  • Fetal movements
42 If induction of labour declined → offer increased fetal monitoring
  • Blood pressure
  • Urinalysis

Extra Information

General Advice / Management

Sleeping Position

Advise women to avoid sleeping on their backs after 28 weeks of pregnancy

  • Rationale: there may be a link between sleeping on the back and stillbirth in late pregnancy
  • Consider using pillows to maintain their position while sleeping

Management of Common Problems During Pregnancy

Problem Management
Nausea and vomiting Reassure that mild to moderate nausea and vomiting are common and are likely to resolve before 16-20 weeks

See the Nausea and Vomiting and Hyperemesis Gravidarum in Pregnancy article for more information.

Heart burn Consider a trial of an antacid or alginate (avoid PPIs)

Offer lifestyle and dietary changes (see the Gastro-Oesophageal Reflux Disease (GORD) article for more information)

Symptomatic vaginal discharge Advise pregnant women who have vaginal discharge that this is common during pregnancy.

However, the presence of symptoms (e.g. itching, soreness, offensive smell, dysuria) may indicate an underlying infection.

Pelvic girdle pain Consider referral to physiotherapy for exercise advice and/or non-rigid lumbopelvic belt
Unexplained vaginal bleeding after 13 weeks Refer to secondary care

Offer anti-D immunoglobulin if they are rhesus D-negative AND at risk of isoimmunisation

Routine Checks

Key routine checks:

Check Purpose
Blood pressure Screen for gestational hypertension / pre-eclampsia (see the Hypertension in Pregnancy article for more information)
Urinalysis Screen for proteinuria (possible pre-eclampsia) and asymptomatic bacteruia which requires active treatment (see the Urinary Tract Infection (UTI) in Adults article for more information)
SFH Monitor fetal growth

Check for growth restriction or macrosomia

Fetal movements Assess fetal wellbeing

See the Reduced Fetal Movement (RFM) article for more information

Combined Test and Anomaly Scan

More details are discussed in the Fetal Anomaly Screening Programme article.

Anti-D Prophylaxis

Routine antenatal anti-D prophylaxis (RAADP) is recommended for all pregnant women who are: [Ref]

  • Rhesus D negative (confirmed on blood group typing), AND
  • Not known to be sensitised to the RhD antigen (confirmed on antibody screen / indirect Coombs test)

Dosing: [Ref]

  • Most common: 2 doses of anti-D immunoglobulin: one at 28 weeks and one at 34 weeks
  • Single dose at 28 weeks OR between 28-30 weeks is also possible

Vaccines in Pregnancy

4 main vaccines are recommended in pregnancy

  • Seasonal flu vaccine (any trimester)
  • COVID-19 vaccine (recommended throughout pregnancy)
  • Pertussis (whooping cough) vaccine – ideally 20-30 weeks
  • RSV vaccine – from 28 weeks (protects baby from serious RSV in the first month)

References

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