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Subdural Haemorrhage (SDH)

Emergency Neurological Life Support Traumatic Brain Injury Protocol Version 6.0. Last updated: Dec 2024.

Brain Trauma Foundation Guidelines for the Surgical Management of TBI. Mar 2006.

NICE guideline [NG232] Head injury: assessment and early management. Published: May 2023.

Subdural Haemorrhage (SDH)

Subdural haemorrhage (SDH) is an extra-axial intracranial haemorrhage occurring between the dura and arachnoid mater.

This updated UKMLA guide to SDH covers acute subdural haemorrhage, chronic subdural haemorrhage, causes, risk factors, symptoms, diagnosis, and management.

Definition and Anatomy

Intracranial haemorrhage is a broad term referring to any bleeding within the skull (cranial vault). It can be categorised into:

Extra-axial haemorrhage = bleeding outside the brain parenchyma Intra-axial haemorrhage = bleeding within the brain parenchyma
Which includes:

  • Extradural haemorrhage (EDH)
  • Subdural haemorrhage (SDH)
  • Subarachnoid haemorrhage (SAH)
Which includes:

  • Intracerebral haemorrhage
  • Intraventricular haemorrhage

Overview of Intracranial Extra-Axial Haemorrhage

The 3 main extra-axial haemorrhages:

Haemorrhage type Location Typical cause / source Classic CT appearance High-yield clinical presentation
Extradural haemorrhage (EDH) Between the skull and dura Middle meningeal artery Biconvex / lens-shaped hyperdense mass Head injury followed by a possible lucid interval, then rapid deterioration
Subdural haemorrhage (SDH) Between the dura and arachnoid Bridging veins Crescent-shaped mass (hyperdense in acute; hypodense in chronic) Confusion, focal neurology, reduced GCS, esp. in elderly, alcohol excess, anticoagulation use
Subarachnoid haemorrhage (SAH) Between the arachnoid and pia Ruptured aneurysm Hyperdense signal in the sulci, fissures, or basal cisterns Thunderclap headache, meningism, reduced GCS

Causes and Risk Factors

There are 2 types of SDH, with different pathophysiology, causes and risk factors: [Ref1][Ref2]

Feature Acute subdural haemorrhage Chronic subdural haemorrhage
Description Acute bleeding into the subdural space, usually occurring immediately after head injury A delayed collection of fluid and blood that can present weeks, months, or even years after an initial event
Pathophysiology Tearing / rupture of bridging veins due to mechanical or shearing forces Currently understood as a complex cerebrovascular disease.

A minor dural injury triggers an inflammatory cascade, recruiting fibroblasts and angiogenic growth factors. This grows a leaky, incompetent “neovasculature” that continuously exudes blood and fluid.

Causes
  • Blunt trauma / traumatic brain injury (e.g. motor vehicle accidents, falls, assaults) – leading cause in adults
  • Spontaneous SDH is uncommon [Ref]
  • Often originates from a minor injury that was unrecognised
  • May evolve from an initial acute or subacute haemorrhage that was unrecognised
Risk factors
  • Male adolescence (due to high risk of accidental trauma)
  • Advanced age (cerebral contraction and brain atrophy stretch the bridging veins)
  • Causes of brain atrophy (e.g. Alzheimer’s disease)
  • Use of anticoagulants or antiplatelets
  • Underlying coagulopathies (including liver disease, kidney disease, cancer)

Clinical Features

Patients with repeated trauma / underlying coagulopathy are more likely to develop chronic SDH or acute-on-chronic SDH.

Acute Subdural Haemorrhage

Acute SDH usually presents shortly after head trauma, and has a wide spectrum of presentation: [Ref]

  • Asymptomatic
  • Headache
  • Confusion, agitation or drowsiness
  • Focal neurological deficits
  • Seizures
  • Reduced GCS

Acute SDH can rapidly expand in the subdural space and can cause raised ICP and can lead to uncal herniation: [Ref]

  • Cushing reflex – triad of ↑ BP (or wide pulse pressure) + bradycardia + irregular breathing (Cheyne-Stokes breathing)
  • Ipsilateral fixed, dilated pupil or asymmetrical pupils (due to CN III compression)
  • Contralateral upper motor neuron lesion signs

Chronic Subdural Haemorrhage

A chronic SDH often undergoes a “latent stage” that can last for weeks, months, or even years after a minor initial injury. [Ref]

Once the accumulation of fluid and blood grows large enough, the patient enters the “clinical stage” and manifests clinically, ranging from: [Ref]

  • Cognitive decline
  • Altered mental status
  • Headaches
  • Focal neurological deficits
  • Aphasia
  • Seizures
  • New or recurrent signs of raised ICP

Assessment and Management

Shared Investigation and Diagnosis

1st line investigation: non-contrast CT head

Classic CT finding
  • Crescent-shaped mass
  • Location: extra-axial (on the edge of the skull)
  • Memory aid: SDH can look like a “banana” on CT
Other radiographic features
  • The haemorrhage can cross the cranial suture lines
  • Possible associated skull fractures
  • Large haemorrhages can cause mass effect
Acute vs chronic SDH
  • Acute = hyperdense (bright / white)
  • Chronic = hypodense (dark)

Acute Subdural Haemorrhage Approach

Since most acute SDHs result from blunt head trauma / traumatic brain injury, initial assessment and management should follow a standard TBI approach.

Imaging should be performed urgently once the primary survey is complete, and the patient is stable enough for imaging.

Primary Survey (Initial Management)

A-E primary survey and management (to be started pre-hospitally and continued in the hospital):

Component Assessment and investigations Management
A & B – Airway and breathing
  • Assess airway patency
  • Monitor oxygen saturation
  • Secure the airway
  • Rapid-sequence intubation if post-resuscitation GCS is 8 or less
  • Maintain oxygenation (≥94%)
  • Target normal ventilation
C – Circulation
  • Monitor BP
  • FAST exam to check for internal bleeding
  • Clotting studies (PT/aPTT/INR, platelet, fibrinogen)
  • Obtain IV or IO access
  • Avoid hypotension
  • Maintain systolic BP ≥100-110 mmHg
  • Correct any coagulopathies
    • If on warfarin → IV vitamin K + PCC
    • If on apixaban / rivaroxaban → andexanet alfa
    • If on dabigatran → idarucizumab
    • If on heparin → protamine sulfate
    • If patient on antiplatelets → platelet transfusion +/- desmopressin
D – Disability
  • Calculate GCS
  • Assess pupil (size, shape and reactivity)
  • Cervical collar and maintain strict spinal immobilisation until cervical spine stability can be established
E – Exposure
  • Expose the patient properly to assess for traumatic injuries
  • Maintain normothermia
  • Avoid prolonged exposure as it can result in hypothermia

Indications for Urgent CT Head

Perform a non-contrast CT head within 1 hour if ANY of the following are present (based on NICE NG232):

  • GCS ≤12 on initial assessment
  • GCS <15 at 2 hours after injury
  • Suspected open / depressed skull fracture
  • Signs of basal skull fracture
  • Post-traumatic seizure
  • Focal neurological deficit
  • >1 vomiting episode

See the Head Injury in Adults article for other indications of CT.

Acute SDH-Specific Management

Indications for neurosurgical intervention (ANY of the following): [Ref]

  • >10 mm thickness
  • Midline shift >5 mm
  • GCS ≤8 PLUS decline in GCS ≥2 points OR asymmetric / non-reactive pupils

Standard procedure (in comatose patients): craniotomy with haematoma evacuation

Complication / other management: [Ref]

Clinical aspect / complication Management
ICP monitoring Insertion of an ICP monitor is indicated with ANY of the following:

  • Abnormal CT + GCS ≤8
  • Normal CT + GCS ≤8 + at least 2 of the following
    • >40 y/o
    • Motor posturing
    • Systolic BP <90 mmHg
Raised ICP If monitored, ICP >22 mmHg requires prompt treatment:

  • Initial steps
    • Elevate the bed to 30 degrees
    • Optimise sedation and analgesia
  • Hyperosmolar therapy (mannitol or hypertonic saline)
  • Consider temporary hyperventilation
Seizure prophylaxis Cortical irritation from the blood increases the risk of seizures.

Levetiracetam is the preferred medication

Do NOT routinely perform or give the following:

  • Corticosteroids
  • Prophylactic hypothermia
  • Prophylactic hyperventilation (in the absence of signs of raised ICP and brain herniation)

Chronic Subdural Haemorrhage Approach

Assessment and Work-Up

1st line: non-contrast CT head

Management

Observation and non-surgical management are often recommended for patients who are asymptomatic or only mildly symptomatic, particularly those who are at surgical risk [Ref]

Conservative management usually involves: [Ref]

  • Reviewing anticoagulant and antiplatelet use, balancing the risks and benefits of continuing vs withholding treatment
  • Serial follow-up CT scans to monitor for stability, resolution or recurrence
  • Close neurological monitoring and safety-netting for worsening symptoms

Neurosurgical intervention is typically considered if: [Ref]

  • Thickness >10 mm, or
  • Midline shift >5 mm

References

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