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Vasa Praevia

RCOG Vasa Praevia: Diagnosis and Management (Green-top Guideline 27b). Last reviewed: Sep 2018.

Definition

Vasa praevia is a condition in which the fetal blood vessels run through the membranes overlying the cervical os, leaving them unprotected by the placental tissue or umbilical cord (Wharton’s jelly).

The fetal vessels are often located near or directly over the cervical os, which makes them highly vulnerable to rupture, particularly when the membranes rupture, either spontaneously or artificially.

Aetiology

Primary risk factors:

  • Velamentous cord insertion – most common risk factor
  • Placenta praevia or low-lying placenta
  • Placental structural anomalies (e.g. bilobed placenta, placenta with accessory lobes)
  • Assisted reproductive technologies
  • Multiple pregnancies

Clinical Manifestation

Classic presentation: painless vaginal bleeding during labour

  • The bleeding typically occurs when the membrane ruptures (spontaneously or artifically)

Other key signs during labour:

  • Pulsating fetal vessels (detect via vaginal examination)
  • Acute fetal compromise immediately after the membranes rupture

Antenatal bleeding is possible and may suggest vasa praevia. However, it has a very low positive predictive value as bleeding is common in pregnancy, while vasa praevia is rare.

Investigation and Diagnosis

Test of choice: transabdominal and transvaginal colour Doppler imaging

Management

There are 3 main scenarios:

Scenario Recommended management
Asymptomatic women with confirmed vasa praevia (diagnosed prenatally) Planned Caesarean delivery between 34 – 36 weeks of gestation
Patient with known vasa preavia experiences PROM or goes into spontaneous labour Emergency Caesarean section
Vasa praevia unexpectedly diagnosed during active labour

References

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