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Post-Polypectomy Surveillance

British Society of Gastroenterology/Association of Coloproctology of Great Britain and Ireland/Public Health England post-polypectomy and post-colorectal cancer resection surveillance guidelines.

Surveillance Pathways

There are 2 main pathways, depending on 1) histology and 2) macroscopic morphology

Histological Risk Stratification Pathway

High-risk histological findings:

  • ≥2 pre-malignant polyps with ≥1 advanced polyp, or
  • ≥5 pre-malignant polyps

The surveillance pathway depends on whether there are high-risk findings or not:

High-risk finding(s) present → One-off surveillance colonoscopy at 3 years (with further surveillance guided by colonoscopic findings)
NO high-risk findings → Return to national bowel cancer screening programme (no additional colonoscopic surveillance)

Morphology-Based Pathway (LNPCPs)

This pathway only applies to LNPCPs: large (≥20mm), non-pedunculated colorectal polyps. All other polyps should follow the histology-based surveillance pathway (see above).

The surveillance pathway depends on resection and excision status:

Complete (r0) resection + en bloc excision → One-off surveillance colonoscopy at 3 years (with further surveillance guided by colonoscopic findings)
Otherwise → More intense surveillance colonoscopy is necessary:
  • Site-check colonoscopy at 2-6 months,
  • Then, repeat at 12 months,
  • Then, one-off surveillance colonoscopy at 3 years (with further surveillance guided by colonoscopic findings)

Key takeaway: large (≥20mm), non-pedunculated colorectal polyps are associated with a higher risk of incomplete resection and local recurrence.

When Surveillance is Not Recommended

Do not offer routine surveillance if:

  • Life expectancy <10 years
  • Significant comorbidity
  • Very advanced age (e.g. >75 years) (individualised decision)

References

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