Disclaimer
We’re actively expanding Guideline Genius to cover the full UKMLA content map. You may notice some conditions not uploaded yet, or articles that only include diagnosis and management for now. For updates, follow us on Instagram @guidelinegenius.
We openly welcome any feedback or suggestions through the anonymous feedback box at the bottom of every article and we’ll do our best to respond promptly.

Thank you for your support.
The Guideline Genius Team

Total Live Articles: 312

Head Injury

NICE Guideline [NG232] Head injury: assessment and early management. Published: May 2023

The author would like to clarify that only recommendations for >16 y/o are included. Recommendations regarding indications of CT cervical spine are not included.

Background Information

Glasgow Coma Scale (GCS)

GCS Components

Component Response Score
Eye-opening (E) Spontaneous 4
To voice 3
To pain 2
No response 1
Verbal response (V) Alert and oriented 5
Confused 4
Inappropriate words 3
Incomprehensible sounds 2
No response 1
Motor response (M) Obeys command 6
Localised to pain 5
Withdraws from pain 4
Decorticate posture 3
Decerebrate posture 2
Flaccid paralysis 1

 

To report and communicate a patient’s GCS score, report the scoring from each component, but not just the total score:

  • GCS: E4 V5 M6, 15/15
  • GCS: E1 V2 M4, 7/15

GCS Interpretation

GCS ranges from 3-15 (3 being the worst and 15 being the best).

  • Mild TBI: GCS 13-15
  • Moderate TBI: 9-12
  • Severe TBI: 3-8

Guidelines

Assessment and Management in the Emergency Department

Important GCS considerations

  • GCS ≤8intubation often required to protect the airway
  • GCS ≤12 + no suspected extracranial bleeding → consider tranexamic acid
    • 2g IV bolus in adults
    • To be given within 2 hours of the injury

Investigation and Diagnosis

Primary investigation of choice: non-contrast head CT

Criteria for CT within 1 hour

ANY of the following:

  • GCS ≤12 on initial assessment
  • GCS <15 at 2 hours after injury
  • Suspected open / depressed skull fracture
  • Signs of basal skull fracture (haemotympanum, panda eyes, CSF leakage from the nose / ear, Battle’s sign)
  • Post-traumatic seizure
  • Focal neurological deficit
  • >1 vomiting episode

Criteria for CT within 8 hours

Presence of loss of consciousness / amnesia after the injury + any of the following:

  • ≥65 y/o
  • Presence of clotting / bleeding disorders
  • Dangerous mechanism of injury
  • >30 min retrograde amnesia

If patients present >8 hours after the injury, perform the head CT within 1 hour.

Patient Taking Anticoagulant / Antiplatelet – excluding aspirin monotherapy

In the absence of other indications → CT head within 8 hours (or within 1 hour if presented >8 hours).

Admission and Observation

Admission Criteria

  • New clinically important abnormalities on imaging (an isolated simple linear non-displaced skull fracture is unlikely to be a clinically important abnormality unless they are taking anticoagulant or antiplatelet medication)
  • GCS score not returned to baseline / 15 following imaging
  • CT scanning indicated but cannot be done within the appropriate time period
  • Continuing worrying symptoms (e.g. persistent vomiting, severe headaches or seizures)
  • Other sources of concern to the clinician (e.g. drug or alcohol intoxication, other injuries, shock, suspected non-accidental injury, meningism, cerebrospinal fluid leak, or suspicion of ongoing post-traumatic amnesia).

Inpatient Observation

Documented neurological observations should include;

  • GCS score
  • Pupil size and reactivity
  • Limb movements
  • Heart rate and blood pressure
  • Respiratory rate and blood oxygen saturation
  • Temperature

Observation frequency:

  • Half-hourly until GCS of 15
  • Once GCS is 15
    • Half-hourly for 2 hours, then
    • 1 hourly for 4 hours, then
    • 2 hourly

References

Original Guidelines

Share Your Feedback Below

UK medical guidelines made easy. From guidelines to genius in minutes!

Quick Links

Cookie Policy

Social Media

© 2026 GUIDELINE GENIUS LTD