Dysmenorrhoea
NICE CKS Dysmenorrhoea. Last Revised Oct 2023.
Article Last Updated:28/11/2025
Background Information
Definition and Types
Dysmenorrhoea: painful lower abdominal cramping that occurs shortly before and/or during menstruation.
2 types of dysmenorrhoea:
- Primary dysmenorrhoea: absence of any identifiable underlying pelvic pathology + begins 6-12 months after menarche
- Thought to be caused by the production of uterine prostaglandins during menstruation
- Secondary dysmenorrhoea: caused by an underlying pelvic pathology + begins after a few years of painless period
Causes
Causes of secondary dysmenorrhoea include:
- Endometriosis
- Adenomyosis
- Fibroids
- Pelvic inflammatory disease
- Intrauterine device insertion
- Ovarian / cervical cancer
Guidelines
Diagnosis
Primary dysmenorrhoea is a diagnosis of exclusion (secondary causes have to be ruled out clinically and/or via investigations)
Conduct:
- History
- Examinations: abdominal & pelvic
Consider the following
- Ultrasound
- If at risk of STIs → STI screen (inc. high vaginal & endocervical swabs)
- Pregnancy test
Features Indicating Primary Dysmenorrhoea
- Onset: typically 6-12 months after menarche
- Pain related to menstruation
- Onset shortly before, improving as menses progresses, lasting up to 72 hours
- Absent gynaecological symptoms
- Other non-gynaecological symptoms may occur
- Normal pelvic examination
Features Indicating Secondary Dysmenorrhoea
- Onset: several years after painless periods
- Pain not consistently related to menstruation
- May persist after menstruation finishes OR
- Present throughout cycle, but exacerbated by menstruation
- Presence of gynaecological symptoms
- Abnormal pelvic examination
- NB – normal examination does NOT exclude secondary dysmenorrhoea
Management
Primary Dysmenorrhoea
Non-pharmacological Management
Consider:
- Local application of heat
- TENS
Pharmacological Management
1st line options:
- NSAID, or
- If patient does not wish to conceive: combined oral contraceptive for 3-6 months trial
If insufficient response to 1st line options → consider combining the 2 above and adding paracetamol.
Referral Criteria
Refer to gynaecologist if:
- Severe symptoms + no response to initial treatment within 3-6 months, or
- Doubt about diagnosis
Secondary Dysmenorrhoea
Refer all patients with suspected secondary dysmenorrhea to a gynecologist for further investigation & management
- Management depends on the underlying cause.