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Pneumothorax

NICE Guideline [NG39] Major trauma: assessment and initial management. Published: Feb 2016.

British Thoracic Society (BTS) Guideline for Pleural Disease 2023.

ATLS® Advanced Trauma Life Support® Student Course Manual 10th Edition. 2018 American College of Surgeons.

Pneumothorax

This updated UKMLA guide covers both spontaneous pneumothorax and tension pneumothorax, based on BTS guidelines.

Definitions

Spontaneous pneumothorax: presence of air in the pleural space, between the visceral and parietal pleura, that occurs in the absence of trauma or medical intervention.

Tension pneumothorax is a life-threatening condition characterised by intrapleural pressure rising sufficiently to cause significant hemodynamic compromise, typically due to a one-way valve effect that traps air in the pleural space.

Causes and Risk Factors

Causes of pneumothorax are classically divided into the following: [Ref1][Ref2]

Type Causes
Spontaneous Spontaneous pneumothorax occurs spontaneously, without any preceding trauma / medical intervention.

Spontaneous pneumothorax can be sub-classified into:

  • Primary spontaneous pneumothorax (PSP): occurs in otherwise healthy individuals without known lung diseases
    • Risk factor: young, tall, thin males
    • Most have subclinical lung abnormalities (e.g. subpleural blebs and bullae)
  • Secondary spontaneous pneumothorax (SSP): occurs in individuals with underlying lung disease (e.g. COPD, asthma, cystic fibrosis) OR ≥50 y/o with a significant smoking history
    • These patients’ alveoli are more prone to rupture from chronically increased alveolar pressure or lung tissue necrosis
Traumatic
  • Penetrating chest trauma (e.g. gunshot wound, stab wound)
  • Blunt chest trauma (e.g. motor vehicle accident)
Iatrogenic
  • Mechanical ventilation
  • Central venous catheter placement
  • Thoracocentesis
  • Lung biopsy
  • Bronchoscopy

Any type of pneumothorax can evolve into tension pneumothorax; however the risk is greater in traumatic and iatrogenic pneumothorax[Ref]

Risk is highest in mechanically ventilated patients. [Ref]

Complication

Acute Complications

  • Progression into tension pneumothorax
    • Any type of pneumothorax can evolve into tension pneumothorax, however the risk is greater in traumatic and iatrogenic pneumothorax [Ref]
    • Risk is highest in mechanically ventilated patients [Ref]
  • Persistent air leak / failure of lung re-expansion
  • Respiratory failure
  • Obstructive shock (mostly seen in tension pneumothorax, where the mediastinal shift compresses the great veins and reduces preload)

Chronic Complications

  • Recurrence is common (>50% recurrence risk after 1st episode, higher in the presence of underlying lung disease)
  • Persistent air leak and failure of lung re-expansion

Diagnosis

Clinical Features

Symptoms

Sudden onset of:

  • Pleuritic chest pain
  • Dyspnoea

Signs

Typical respiratory examination findings:

Examination aspect Typical findings
Chest expansion  on the affected side (due to pain)
Percussion Hyper-resonant over the affected area
Tactile fremitus ↓  on the affected side
Auscultation Reduced / absent breath sound over the affected area

Additional findings that suggest tension pneumothorax:

  • Haemodynamic instability
  • Tracheal deviation (away from the affected side) and distended neck veins
    • Typical signs but have low sensitivity
    • Absence does NOT exclude diagnosis

Investigation and Diagnosis

1st line: chest X-ray (PA and lateral views)

  • Typical finding is a visible pleural line with lung markers only visible up to this line, no longer visible beyond the pleural line

2nd line (if chest X-ray is equivocal): CT chest

Tension pneumothorax should be a clinical diagnosis. Do not delay interventions to obtain imaging if tension pneumothorax is suspected clinically.

In patients with suspected traumatic pneumothorax, consider eFAST as a rapid bedside adjunct to clinical assessment, provided appropriate equipment and expertise are immediately available

  • eFAST can rapidly assess for pneumothorax, haemothorax, pericardial fluid and intra-abdominal free fluid
  • As part of eFAST, lung ultrasound showing absent lung sliding may suggest pneumothorax, but is not diagnostic on its own
  • A negative eFAST does NOT exclude pneumothorax

Management

Tension Pneumothorax

Immediate management: chest decompression with needle decompression or finger thoracostomy

  • Tension pneumothorax secondary to trauma → 4th/5th intercostal space in the mid-axillary line
  • Non-trauma related → either 2nd intercostal space in the mid-clavicular line OR 4th/5th intercostal space in the mid-axillary line

Definitive management: chest drain insertion should always follow initial chest decompression

Tension pneumothorax should be a clinical diagnosis. Do not delay interventions to obtain imaging if tension pneumothorax is suspected.

Regarding the site of needle decompression, it is very unlikely for exam questions to make one choose between the 2nd intercostal space in the mid-clavicular line, and 4th/5th intercostal space in the mid-axillary line.

They are both technically correct (latest ATLS recommends 4th/5th intercostal space in the mid-axillary line in trauma-related tension pneumothorax due to easier access and a higher procedural success rate), and it also depends on the underlying cause of tension pneumothorax (trauma vs non-trauma).

Spontaneous Pneumothorax

Simplified Management Flowchart

Disclaimer: This simplified flowchart omits details regarding whether it is safe to intervene for visual clarity. Refer to the full management algorithm below for complete guidance.

 

Full Management Algorithm

Symptomatic Pneumothorax

Assess for any of the following high-risk characteristics to determine subsequent steps:

Patient factors
  • ≥50 y/o with significant smoking history
  • Presence of underlying lung disease (i.e. secondary pneumothorax)
  • Significant hypoxia
Pneumothorax factors
  • Haemodynamic compromise
  • Bilateral pneumothorax
  • Haemopneumothorax
High-Risk Characteristics Present

Determine whether it is safe to intervene

  • Yes → chest drain insertion
  • No → perform CT scan and reassess (chest drain insertion is safe under CT guidance irrespective of size)

Subsequent care following chest drain insertion

  • Admit as inpatient with daily review
  • Remove chest drain when resolved
  • Discharge and review as outpatient in 2-4 weeks
No High-Risk Characteristics

Determine whether it is safe to intervene

  • Yes → offer a choice of conservative management or interventional options, depending on the goal outlined below
  • No → only offer conservative management

Management options:

Goal Recommended initial management Description
Patient wishes to avoid procedures Conservative management
  • PSP→ review as outpatient every 2-4 days
  • SSP → admit as inpatient and give high-flow oxygen
Rapid symptomatic relief Needle aspiration
  • If resolved → discharge and review as outpatient in 2-4 weeks
Rapid symptomatic relief, AND if locally available (esp. in PSP) Ambulatory device
  • Review as outpatient every 2-3 days
  • Remove device when resolved
  • If stable → follow up as outpatient in 2-4 weeks

Failed initial management:

  • Regardless of the initial management approach (conservative / needle aspiration / ambulatory device), if it failed to resolve the pneumothorax → the next step-up is chest drain insertion
  • If chest drain still failed to resolve the pneumothorax → definitive management (usually VATS, see below for more details)

Asymptomatic Or Minimal Symptoms

Always offer conservative care regardless of pneumothorax size

  • If PSP  → discharge and review as outpatient every 2-4 days
  • If SSP  → admit as inpatient for a minimum of 24 hours with supplemental oxygen

Expected pneumothorax resolution time:

  • 1cm pneumothorax → ~10 days
  • 2cm pneumothorax → after 2-3 weeks

Failed initial management:

  • Regardless of the initial management approach (conservative / needle aspiration / ambulatory device), if it failed to resolve the pneumothorax → the next step-up is chest drain insertion
  • If chest drain still failed to resolve the pneumothorax → definitive management (usually VATS, see below for more details)

Post-discharge Advice

  • Return to emergency department immediately if further breathlessness develops
  • Advise smoking cessation to reduce risk of recurrence (see the Smoking Cessation article for more information)
  • Patients can only fly 7 days after full resolution confirmed on CXR
  • Patients should be advised to permanently avoid diving, unless a definitive preventive strategy has been performed (e.g. surgical pleurectomy – see below)

Long Term Definitive Management

Thoracic surgery (usually VATS bullectomy + surgical pleurodesis) is the standard 1st line definitive management option

Indications for thoracic surgery (definitive management), ANY:

Treatment failure (despite chest drain) Suggested by:

  • Persistent air leak (failing to resolve despite 5 to 7 days of chest tube drainage), or
  • Failure of the lung to re-expand
Indications based on the affected patient
  • Pneumothorax occurring during pregnancy
  • High-risk professions where recurrence must be avoided (e.g. divers, airline pilots, military personnel), even after a single pneumothorax
Indications based on the pneumothorax type / characteristics
  • After a first tension pneumothorax
  • Recurrent pneumothoraxes
    • After second ipsilateral pneumothorax
    • After first contralateral pneumothorax
  • After first secondary spontaneous pneumothorax associated with significant physiological compromise
  • Synchronous bilateral spontaneous pneumothorax
  • Spontaneous haemothorax

If thoracic surgery is indicated, but the patient is NOT fit, consider the following:

  • Treatment failure (persistent air leak / failure to re-expand) → autologous blood pleurodesis or endobronchial therapies
  • Prevent recurrence → medical chemical pleurodesis

Medical chemical pleurodesis can be a 1st line alternative to thoracic surgery to prevent recurrence in secondary spontaneous pneumothorax

Further information on thoracic surgery:

Surgical approach 1st line: VATS

  • Benefit: lower hospital length of stay, pain and post-operative complications (compared to open thoracotomy)
  • Risks: slightly higher risk of pneumothorax recurrence and slightly higher need for further treatment (compared to open thoracotomy)

2nd line: open thoracotomy

  • Reserved for those who require the absolute lowest possible risk of recurrence (e.g. high risk professions)
Surgical procedure 2 techniques are used (often in combination):

  • Bullectomy (resection of lung parenchyma – specifically blebs and bullae)
  • Surgical pleurodesis
    • Obliterates the pleural space to prevent future air accumulation even if a new leak develops
    • This is achieved by inducing an inflammatory fusion between the visceral and parietal pleural layers (click to see more)

References

ATLS® Advanced Trauma Life Support® Student Course Manual 10th Edition. 2018 American College of Surgeons.


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