Disclaimer
We’re actively expanding Guideline Genius to cover the full UKMLA content map. You may notice some conditions not uploaded yet, or articles that only include diagnosis and management for now. For updates, follow us on Instagram @guidelinegenius.
We openly welcome any feedback or suggestions through the anonymous feedback box at the bottom of every article and we’ll do our best to respond promptly.

Thank you for your support.
The Guideline Genius Team

Total Live Articles: 326

Dysmenorrhoea

NICE CKS Dysmenorrhoea. Last Revised Oct 2023.

Background Information

Definition and Types

Dysmenorrhoea: painful lower abdominal cramping that occurs shortly before and/or during menstruation.

2 types of dysmenorrhoea:

  • Primary dysmenorrhoea: absence of any identifiable underlying pelvic pathology + begins 6-12 months after menarche
    • Thought to be caused by the production of uterine prostaglandins during menstruation

 

  • Secondary dysmenorrhoea: caused by an underlying pelvic pathology + begins after a few years of painless period

Causes

Causes of secondary dysmenorrhoea include:

  • Endometriosis
  • Adenomyosis
  • Fibroids
  • Pelvic inflammatory disease
  • Intrauterine device insertion
  • Ovarian / cervical cancer

Guidelines

Diagnosis

Primary dysmenorrhoea is a diagnosis of exclusion (secondary causes have to be ruled out clinically and/or via investigations)

Conduct:

  • History
  • Examinations: abdominal & pelvic

Consider the following

  • Ultrasound
  • If at risk of STIs → STI screen (inc. high vaginal & endocervical swabs)
  • Pregnancy test

Features Indicating Primary Dysmenorrhoea

  • Onset: typically 6-12 months after menarche
  • Pain related to menstruation
    • Onset shortly before, improving as menses progresses, lasting up to 72 hours
  • Absent gynaecological symptoms
    • Other non-gynaecological symptoms may occur
  • Normal pelvic examination 

Features Indicating Secondary Dysmenorrhoea

  • Onset: several years after painless periods
  • Pain not consistently related to menstruation
    • May persist after menstruation finishes OR
    • Present throughout cycle, but exacerbated by menstruation
  • Presence of gynaecological symptoms  
  • Abnormal pelvic examination
    • NB – normal examination does NOT exclude secondary dysmenorrhoea

Management

Primary Dysmenorrhoea

Non-pharmacological Management

Consider:

  • Local application of heat
  • TENS

Pharmacological Management

1st line options:

  • NSAID, or
  • If patient does not wish to conceive: combined oral contraceptive for 3-6 months trial

If insufficient response to 1st line options → consider combining the 2 above and adding paracetamol.

Referral Criteria

Refer to gynaecologist if:

  • Severe symptoms + no response to initial treatment within 3-6 months, or
  • Doubt about diagnosis

Secondary Dysmenorrhoea

Refer all patients with suspected secondary dysmenorrhea to a gynecologist for further investigation & management

  • Management depends on the underlying cause.

References

Original Guidelines

Share Your Feedback Below

UK medical guidelines made easy. From guidelines to genius in minutes!

Quick Links

Cookie Policy

Social Media

© 2026 GUIDELINE GENIUS LTD