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Acute Rhinosinusitis

NICE guideline [NG79] Sinusitis (acute): antimicrobial prescribing. Published: Oct 2017.

Background Information

Definition

Rhinosinusitis is a symptomatic inflammation of the mucosal lining of the paranasal sinuses and nasal cavity.

 

Acute vs chronic rhinosinusitis:

  • Acute rhinosinusitis: symptoms that completely resolve within 12 weeks
  • Chronic rhinosinusitis: symptoms lasting 12 weeks or longer

Guidelines

Management

Approach:

  • 1st line: conservative management
  • If no improvement after ≥10 days (or worsening): further management (intranasal steroids or antibiotics)

Step 1: Conservative Management

Do not offer antibiotics. Offer the following for symptomatic relief:

  • Advise that the usual course of acute sinusitis is 2-3 weeks
  • Paracetamol or ibuprofen for pain or fever
  • Patients may try nasal saline or nasal decongestants but the evidence is not strong

Step 2: Further Management

Consider the following (if there is no improvement of symptoms after ≥10 days OR a worsening of symptoms)

  • Intranasal corticosteroids for 14 days

 

  • Antibiotic therapy (back-up) for 5 days
    • 1st line: phenoxymethylpenicillin (penicillin V)
    • Penicillin allergic: doxycycline / clarithromycin / erythromycin (if pregnant)
    • If systemically unwell / features of more serious illness / high risk of complications: co-amoxiclav

The following features are suggestive of bacterial infection (vs viral) in acute sinusitis:

  • Persistent symptoms for ≥ 10 days
  • Discoloured or purulent nasal discharge
  • Severe localised pain (often unilateral, esp. pain over teeth and jaw)
  • Fever > 38°C.
  • Marked deterioration after an initial milder phase (double sickening)

References

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