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Gender Dysphoria and Gender Incongruence

Gender Dysphoria and Gender Incongruence

Terms and Definitions

Core definitions: [Ref]

Term Definition
Gender incongruence State of mismatch or misalignment between a person’s inner gender identity (their psychological sense of their gender) and their assigned sex at birth

Example: A person assigned female at birth (AFAB) whose inner gender identity is male

Gender dysphoria A formal psychiatric diagnosis (defined in the DSM-5-TR) where gender incongruence results in clinically significant psychological distress or impairment in social, occupational, or other important areas of functioning

Some other related terms: [Ref]

Category Terms and definition
Internal and external experience Gender identity: an individual’s inner sense of being a girl / woman, boy / man, some combination of both, or some other gender (which may or may not correspond to their sex assigned at birth)

Gender expression: the outward, public manifestation of a person’s gender (this includes how they carry themselves, their dress, accessories, grooming, voice/speech patterns, and conversational mannerisms)

Core identities Transgender: an umbrella term describing individuals whose gender identity does not align with their assigned sex at birth
  • It can also refer to a person whose gender identity is binary but not traditionally associated with their assigned sex

Cisgender: a term describing an individual whose gender identity aligns with the sex assigned to them at birth

Non-binary: a term describing an individual whose gender identity is neither girl / woman nor boy / man

Medical and physical baselines Sex assigned at birth refers to assignment made at birth, usually based on external genitalia; this includes
  • Assigned female at birth (AFAB)
  • Assigned male at birth (AMAB)

Intersex or disorders of sexual development (DSD): a group of physical medical conditions involving the reproductive system where biological sex characteristics do not fit typical male or female development (e.g. androgen insensitivity syndrome, congenital adrenal hyperplasia, 5-alpha-reductase deficiency)

Sexual orientation: an individual’s erotic attraction or romantic tendencies [Ref]

  • Sexual orientation is distinct from and independent of gender identity
  • Sexual orientations include heterosexual, homosexual, bisexual, or asexual

Gender incongruence is the underlying misalignment that defines being transgender. However, NOT all transgender or gender-diverse individuals experience gender dysphoria.

An individual can live with gender incongruence as part of their identity without experiencing the distressing, clinically significant impact of gender dysphoria.

Clinical Features and Diagnosis

The DSM-5 criteria for gender dysphoria differ between pre-pubertal children and post-pubertal individuals (adolescents and adults).

Patient population DSM-5 criteria
Post-pubertal individuals (adolescents and adults) Marked gender incongruence (state of mismatch or misalignment between a person’s inner gender identity and their assigned sex at birth) for at least 6 months

Characterised by the presence of at least 2 of the following:

  1. Marked incongruence between one’s experienced/expressed gender and primary and/or secondary sex characteristics (or in young adolescents, the anticipated secondary sex characteristics)
  2. Strong desire to be rid of one’s primary and/or secondary sex characteristics because of a marked incongruence with one’s experienced/expressed gender (or in young adolescents, a desire to prevent the development of the anticipated secondary sex characteristics)
  3. Strong desire for the primary and/or secondary sex characteristics of the other gender
  4. Strong desire to be of the other gender
  5. Strong desire to be treated as the other gender
  6. Strong conviction that one has the typical feelings and reactions of the other gender

The above features must be associated with clinically significant distress or impairment in social, occupational, or other important areas of functioning

Pre-pubertal children Marked gender incongruence (state of mismatch or misalignment between a person’s inner gender identity and their assigned sex at birth) for at least 6 months

Characterised by the presence of at least 6 of the following, and the first criterion must be met:

  • Strong desire to be of the other gender or an insistence that one is the other gender
  • In boys (assigned gender), a strong preference for cross-dressing or simulating female attire; or in girls (assigned gender), a strong preference for wearing only typical masculine clothing and a strong resistance to the wearing of typical feminine clothing
  • Strong preference for cross-gender roles in make-believe play or fantasy play
  • Strong preference for the toys, games or activities stereotypically used or engaged in by the other gender
  • Strong preference for playmates of the other gender
  • In boys (assigned gender), a strong rejection of typically masculine toys, games, and activities and a strong avoidance of rough-and-tumble play; or in girls (assigned gender), a strong rejection of typically feminine toys, games, and activities
  • Strong dislike of one’s sexual anatomy
  • Strong desire for the physical sex characteristics that match one’s experienced gender

The above features must be associated with clinically significant distress or impairment in social, occupational, or other important areas of functioning

Referral

[Ref]

≥18 y/o → NHS gender dysphoria clinic

<18 y/o → paediatric or children and young people’s mental health services (who can then refer to NHS children and young people’s gender service)

Management

Key management principles: [Ref]

Age group Management
<18 y/o Treatment is highly restricted
  • Standard treatment: talking therapy and counselling
  • Hormonal and surgical therapy is NOT recommended in pre-pubertal children [Ref]
≥18 y/o Options include:
  • Talking therapy and counselling
  • Voice and communication therapy – delivered by SLT to help a person’s voice and communication better align with their gender identity
  • Medical therapy (hormonal therapy)
    • Masculinising therapy: primarily testosterone
    • Feminising therapy: primarily oestrogen ± androgen-suppressing treatment
  • Surgery (gender reassignment surgery or gender-affirming surgery)
    • Masculinising surgeries include chest masculinisation surgery (bilateral mastectomy with chest reconstruction/contouring), hysterectomy +/- oophorectomy, and genital reconstruction with phalloplasty or metoidioplasty
    • Feminising surgeries include orchidectomy, vaginoplasty and breast augmentation (facial feminisation surgery is NOT available in the NHS)

As medical and surgical treatments can impact future fertility, referrals to fertility services to preserve eggs or sperm prior to starting treatment should be supported

 

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