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Post-Traumatic Stress Disorder (PTSD)

NICE guideline [NG116] Post-traumatic stress disorder. Published: Dec 2018.

Background Information

Causes

PTSD could develop after experiencing or witnessing:

  • Serious accidents
  • Physical and sexual assault
  • Abuse, including childhood or domestic abuse
  • Work-related exposure to trauma, including remote exposure
  • Trauma related to serious health problems or childbirth experiences (for example, intensive care admission or neonatal death)
  • War and conflict
  • Torture

Guidelines

Recognition

Some common symptoms:

  • Re-experiencing
  • Avoidance
  • Hyperarousal (including hypervigilance, anger and irritability)
  • Negative alterations in mood and thinking
  • Emotional numbing
  • Dissociation
  • Emotional dysregulation
  • Interpersonal difficulties or problems in relationships
  • Negative self-perception (including feeling diminished, defeated or worthless)

Management

Consider active monitoring for those with subthreshold PTSD symptoms within 1 month of a traumatic event.

Do not offer psychologically-focused debriefing for the prevention or treatment of PTSD

Children and Young People

Psychological Therapy

  • ​​​1st line: individual trauma-focused CBT
    • Consider group trauma-focused CBT if the event led to large-scale shared trauma
  • 2nd line: eye movement desensitisation and reprocessing (EMDR)
    • Indicated >3 months of traumatic event AND a lack of enagement/response to CBT

Pharmacological Management

Do not offer drug treatments for the prevention or treatment of PTSD in children and young people aged under 18 years

Adults

Psychological Therapy

1st line: individual trauma-focused CBT interventions:

  • Cognitive processing therapy
  • Cognitive therapy for PTSD
  • Narrative exposure therapy
  • Prolonged exposure therapy

Eye movement desensitisation and reprocessing (EMDR) can be considered/offered in non-combat related trauma in the following scenarios:

  • Consider if 1-3 months post-traumatic event AND preference for EMDR
  • Offer if >3 months post-traumatic event

EMDR is not excluded from use in combat trauma-related PTSD, but its research base and clinical implementation is less extensive compared to civilian/non-combat trauma.

Pharmacological Management

1st line: SSRI (e.g. sertraline) or venlafaxine

Consider antipsychotics (e.g. risperidone) in addition to psychological therapies to manage symptoms if:

  • Disabling symptoms and behaviours (e.g. severe hyperarousal or psychotic symptoms) and
  • Failed to respond to other drug or psychological treatments

References

Original Guideline

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