Disclaimer
We’re actively expanding Guideline Genius to cover the full UKMLA content map. You may notice some conditions not uploaded yet, or articles that only include diagnosis and management for now. For updates, follow us on Instagram @guidelinegenius.
We openly welcome any feedback or suggestions through the anonymous feedback box at the bottom of every article and we’ll do our best to respond promptly.

Thank you for your support.
The Guideline Genius Team

Total Live Articles: 312

Scrotal Lump and Swelling

NICE CKS Scrotal pain and swelling. Last revised: Aug 2024.

Aetiology

A good way to approach the differentials of scrotal lump / swelling is by determining if there is pain or not.

Causes of Painless Scrotal Lump / Swelling

The following causes are most commonly completely painless, or occasionally associated with a dull ache or heaviness if the mass / swelling is significant.

Important causes:

Feature Testicular tumour Epididymal cyst Hydrocele Varicocele Inguinal hernia (into the scrotum)
Transillumination No Yes (hydrocele > epididymal cyst) No
Ability to “get above” lump Yes No (extends above into the inguinal canal)
Key features
  • Hard, irregular mass fixed to the testis
  • Testis palpable
  • Fluctuant mass separated from the testis
  • Testis palpable
  • Diffusefluctuant scrotal swelling
  • Testis not palpable
  • Bag of worms appearance
  • Collapse upon lying down
  • More prominent  with standing/Valsalva
  • Cough impulse present
  • May disappear upon lying down

May be painful if incarcerated / strangulated

Less common causes of painless scrotal lump / swelling:

Cause Description Clinical features
Haematocele A hydrocele filled with blood
  • Occurs following trauma
  • Usually painful and tender
  • May transilluminate (to a lesser extent than a hydrocele)
Spermatocele An epididymal cyst that contains spermatozoa (on histology)
  • Similar to an epididymal cyst
Squamous cell carcinoma of the scrotum Extremely rare
  • Painless raised papule / plaque / ulcer, or
  • Non-healing skin lesion

Causes of Painful Scrotal Lump / Swelling

There are 2 important causes of painful scrotal lump / swelling:

Feature Testicular torsion Epididymo-orchitis
Typical age Teenagers & young men (12–25 yrs) Sexually active adults or older men
Onset Sudden onset Gradual onset over hours to days
Clinical features
  • Severe pain in the entire testis
  • Pain may radiate to the groin
  • N&V is common
  • Pain mainly in the posterior aspect (epididymis)
  • Fever
  • Dysuria / urethral discharge possible
Position of the testis High-riding testis (affected testis appears elevated) Normal
Cremasteric reflex Absent Present
Prehn’s sign (pain relief on testis elevation) Negative – pain not relieved Positive – pain often improves

See the Testicular Torsion and Epididymo-Orchitis articles for more information.

 

The following causes can also be painful (although covered in the painless section above):

  • Incarcerated / strangulated inguinal hernia
  • Haematocele

Investigations

Testicular torsion should be suspected and excluded in any patient presenting with acute scrotal pain and/or swelling, before considering any other causes

 

1st line investigation for scrotal swelling: ultrasound

Indications for urgent ultrasound (outpatient basis) ANY of the following, provided the swelling is NOT of acute onset:
  • Diagnostic uncertainty
  • Persistent, unexplained testicular symptoms
  • Not possible to distinguish if the scrotal swelling is testicular or extra-testicular
  • Hydrocele in 18-40 y/o (due to the possibility of testicular cancer)
  • History of trauma and scrotal pain
Do not arrange an ultrasound if
  • Testicular torsion / acute epididymo-orchitis / strangulated inguinal hernia suspected → urgent hospital admission / referral
  • Testicular cancer supsected clincially → urgent urology referral (cancer pathway) – urology will then arrange the ultrasound

Management

Management depends on the underlying cause, see the corresponding articles:

References

Share Your Feedback Below

UK medical guidelines made easy. From guidelines to genius in minutes!

Quick Links

Cookie Policy

Social Media

© 2026 GUIDELINE GENIUS LTD